Stock ID | SD02599 |
Strain Name | DRH1g∆∆ D3-11F |
AKA | |
Species | T. thermophila |
Genetic Description | drh1[∆?::neo4]/drh1[∆?::neo4] (drh1[∆?::neo4]/drh1[∆?::neo4]; pm-r, ?) |
MAC Knockins/outs | neo4 at 5’ end of coding, some coding remains |
MIC Knockins/outs | neo4 at 5’end of coding, some coding remains |
Gene of Interest | DRH1 (TTHERM_00190830) |
Origin | |
Publications | |
Comments | Homozygous homokaryon KO of DRH1 with neo4 cassette. Mates with DRH1g∆∆ C10-11F Gene is Dicer Related Helicase, sequence is fromTGD 69.m00174. Mating cells stop at mic selection after MeiosisII Gene is expressed at low level in starve and log, peak expression at 4 hr of conjugation. Somatic KO is complete, when mated they arrest after Meiosis II. Homozygous homokaryon KOs do not grow well. Needs Cd for pm resistance. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. |
Research Resource Identifier | TSC_SD02599 |
Requires MTA? | No |
Academic cost | $45 |