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Stock IDSD02464
Strain NameHTA3-T89K
AKA
SpeciesT. thermophila
Genetic Descriptionhtaz[βˆ†::neo2]/htaz[βˆ†::neo2]; mpr1-1/MPR1-1? (htaz[βˆ†::neo2]/htaz[K4R,K7R,K10R,K13R,K16R,K21R, K23Q, K24Q]; pm-r)
MAC Knockins/outsHTAZ coding replaced with mutations K4R, K7R,K10R,K13R,K16R,K21R,K23Q, K24Q
MIC Knockins/outsNeo2 in HTAZ
Gene of InterestHTA3 (TTHERM_00143660)
Origin
PublicationsRen, Q. and M. A. Gorovsky. 2003. The Non-essential H2A N-terminal Tail Can Function as an Essential Charge Patch on the H2A.Z Variant N-terminal Tail. Mol. Cell. Biol., 23:2778-2789.
Ren, Q. and M.A. Gorovsky. 2001. Histone H2A.Z Acetylation Modulates an Essential "Charge Patch". Mol. Cell, 7: 1329-1335.
CommentsG304A1xG311A1 βˆ†HTA3 knockout heterokaryon. Rescued with HTAZ mutated RRRRRRQQ. Slow growth.

From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.
Research Resource IdentifierTSC_SD02464
Requires MTA?No
Academic cost $35