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Stock IDSD02392
Strain NameHTA1-D18C1
AKA
SpeciesT. thermophila
Genetic Descriptionhta1[∆::neo2]/hta1[∆::neo2]; hta2[∆::neo2]/ hta2[∆::neo2]; CHX1/CHX1;mpr1?/mpr1? (hta1[ S1P,K5R,K8R,K10R,k12R, K17R]; hta2[∆::neo2]; pm-r, ?)
MAC Knockins/outsmutated HTA1
MIC Knockins/outsNeo 2 knockout of HTA1 and HTA2 genes
Gene of InterestHTA1 (TTHERM_00790790) + HTA2 (TTHERM_00316500)
OriginQinghu Ren
PublicationsRen Q and Gorovsky MA. 2003. The nonessential H2A N-terminal tail can function as an essential charge patch on the H2A.Z variant N-terminal tail. Mol Cell Biol 23(8):2778-89.

Ren Q and Gorovsky MA. 2001. Histone H2A.Z acetylation modulates an essential charge patch. Mol Cell 7(6):1329-35.
CommentsG4B1G10A x G4B3C1A. HTA.1 S1P plus all K changed to R in N-terminus used to rescue ∆HTA1∆HTA2 double knockout heterokaryon. Abolishes all acetylation.

From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.
Research Resource IdentifierTSC_SD02392
Requires MTA?No
Academic cost $35