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Stock IDSD02385
Strain NameHTA1 S134A rescue ∆∆ 1-1 (2)
AKA
SpeciesT. thermophila
Genetic Descriptionhta1[∆::neo2]/hta1[∆::neo2]; hta2[∆::neo2]/ hta2[∆::neo2]; CHX1/CHX1;mpr1?/mpr1? (hta1[ S134A]; hta2[∆::neo2]; pm-r, ?)
MAC Knockins/outsmutated HTA1
MIC Knockins/outsNeo 2 knockout of HTA1 and HTA2 genes
Gene of InterestHTA1 (TTHERM_00790790) + HTA2 (TTHERM_00316500)
OriginXiaoyuan Song
PublicationsSong X, Gjoneska E, Ren Q, Taverna SD, Allis CD, Gorovsky MA. 2007. Phosphorylation of the SQ H2A.X motif is required for proper meiosis and mitosis in tetrahymena thermophila. Mol Cell Biol 27(7):2648-60.

Ren Q and Gorovsky MA. 2001. Histone H2A.Z acetylation modulates an essential charge patch. Mol Cell 7(6):1329-35.
CommentsIt is somatic rescue of strain of HTA1,HTA2 double knockout by HTA1 S134A mutation. Same mating type as 1-1(3)

From the Gorovsky lab, University of Rochester.
Research Resource IdentifierTSC_SD02385
Requires MTA?No
Academic cost $35