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Stock IDSD02169
Strain NameHTA1wt rescue Double knockout∆∆ 1-4(3)
AKA
SpeciesT. thermophila
Genetic Descriptionhta1[∆::neo2]/hta1[∆::neo2]; hta2[∆::neo2]/ hta2[∆::neo2]; CHX1/CHX1;mpr1?/mpr1? (HTA2 has neo2; pm-r, ?)
MAC Knockins/outsWT HTAX
MIC Knockins/outsNeo 2 knockout of HTAX and HTA1 genes
Gene of InterestHTA1 (TTHERM_00790790), HTA2 (TTHERM_00316500)
OriginXiaoyuan Song
PublicationsSong X, Gjoneska E, Ren Q, Taverna SD, Allis CD, Gorovsky MA. 2007. Phosphorylation of the SQ H2A.X motif is required for proper meiosis and mitosis in tetrahymena thermophila. Mol Cell Biol 27(7):2648-60.

Ren Q and Gorovsky MA. 2003. The nonessential H2A N-terminal tail can function as an essential charge patch on the H2A.Z variant N-terminal tail. Mol Cell Biol 23(8):2778-89.
CommentsIt is HTA1 WT somatic rescue strain of HTA1,HTA2 double knockout. Can mate with 1-5(12).

From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.
Research Resource IdentifierTSC_SD02169
Requires MTA?No
Academic cost $35