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Stock IDSD02074
Strain NameHTA3-T22M3
SpeciesT. thermophila
Genetic Descriptionhtaz[βˆ†::neo2]/htaz[βˆ†::neo2]; mpr1-1/MPR1-1? (htaz[βˆ†::neo2]/htaz[K4Q,K7R,K10Q,K13Q,K16Q,K21Q]; pm-r, ?)
MAC Knockins/outsHTAZ coding replaced with mutations K4Q,K7R,K10Q,K13Q,K16Q,K21Q
MIC Knockins/outsNeo2 in HTAZ
Gene of InterestHTA3 (TTHERM_00143660)
OriginQinghu Ren
PublicationsRen Q and Gorovsky MA. 2003. The nonessential H2A N-terminal tail can function as an essential charge patch on the H2A.Z variant N-terminal tail. Mol Cell Biol 23(8):2778-89.

Ren Q and Gorovsky MA. 2001. Histone H2A.Z acetylation modulates an essential charge patch. Mol Cell 7(6):1329-35.
Comments G304A1xG311A1 βˆ†HTA3 knockout heterokaryon. Rescued with HTAZ mutated QRQQQQ. Slow growth.

From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.
Research Resource IdentifierTSC_SD02074
Requires MTA?No
Academic cost $35