Stock ID | SD01997 |
Strain Name | ∆HTAY pXS83-33 |
AKA | |
Species | T. thermophila |
Genetic Description | (HTAY?/htay[∆::neo3]; MTT1/mtt1[5’neo2, ∆, 2HAn(::HTAY)]; pm-r, ?) |
MAC Knockins/outs | Neo3 KO of HTAY (may be incomplete) and HTAY with two HA tags on the N-terminus inserted into MTT1 locus with neo2 cassete in 5’ flanking region |
MIC Knockins/outs | |
Gene of Interest | H2A.Y (TTHERM_01079200) |
Origin | Xiaoyuan Song |
Publications | Song X, Bowen J, Miao W, Liu Y, Gorovsky MA. 2012. The nonhistone, N-terminal tail of an essential, chimeric H2A variant regulates mitotic H3-S10 dephosphorylation. Genes Dev 26(6):615-29. |
Comments | Transformed pXS83 (MTT-neo2-2HA-HTAY-MTT) into HTA.Y real (true, longer coding seq.) somatic knockout strain in MTT1 locus. Selected in the presence of Cd +Pm. PCR shows very faint band of WT HTA.Y. Same as pXS83-23. Grow in 100ug/ml pm, 0.25 ug/ml CdCl2. From the Gorovsky lab, University of Rochester. This strain has been catalogued by the Stock Center, but not thawed. |
Research Resource Identifier | TSC_SD01997 |
Requires MTA? | No |
Academic cost | $45 |