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We are now shipping live cells, plasmids, genomic DNA, and media packets, although shipping may take somewhat longer than normal. Contact us with any questions.

Stock IDSD01726
Strain NameLH6
SpeciesT. thermophila
Genetic Description(mlh1[243::neo2]; ΔMic LH, enlarged mic, pm-r, II)
MAC Knockins/outsNeo2 cassette inserted into coding of MLH1
MIC Knockins/outs
Gene of InterestMLH1 (TTHERM_00471820)
OriginXuetong Shen
PublicationsShen X, Yu L, Weir JW, Gorovsky MA. 1995. Linker histones are not essential and affect chromatin condensation in vivo. Cell 82(1):47-56.
CommentsTransformation of CU428xB2086, complete knockout of mic histone linker gene with neo2 cassette inserted into Stu1 site. Paromomycin resistant to 2 mg/ml. Cell lines LH3 and LH6 can mate with each other.

Codes for the linker histone found in Mics, present instead of histone H1 as found in macs.

From the Gorovsky Lab, University of Rochester.
Research Resource IdentifierTSC_SD01726
Requires MTA?No
Academic cost $45