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Stock IDSD01785
Strain NameMS-1
SpeciesT. thermophila
Genetic Descriptionchx1-1/chx1-1; sec/sec (sec-, cy-r, II)
MAC Knockins/outs
MIC Knockins/outs
Gene of Interest
PublicationsHunseler P and Tiedtke A. 1992. Genetic characterization of the secretory mutant MS-1 of tetrahymena thermophila: Vacuolarization and block in secretion of lysosomal hydrolases are caused by a single gene mutation. Dev Genet 13(2):167-73.

Hunseler P, Tiedtke A, von Figura K. 1988. Biosynthesis of secreted beta-hexosaminidase in tetrahymena thermophila. A comparison of the wild type with a secretory mutant. Biochem J 252(3):837-42.

Hunseler P, Scheidgen-Kleyboldt G, Tiedtke A. 1987. Isolation and characterization of a mutant of tetrahymena thermophila blocked in secretion of lysosomal enzymes. J Cell Sci 88 ( Pt 1):47-55.
CommentsBlock in secretion is caused by a single gene mutation. Block in secretion and the expression of a vacuolarized phenotype are most probably controlled by the same sec allele. Low fertility.
Research Resource IdentifierTSC_SD01785
Requires MTA?No
Academic cost $35