Stock ID | SD01785 |
Strain Name | MS-1 |
AKA | |
Species | T. thermophila |
Genetic Description | chx1-1/chx1-1; sec/sec (sec-, cy-r, II) |
MAC Knockins/outs | |
MIC Knockins/outs | |
Gene of Interest | |
Origin | |
Publications | Hunseler P and Tiedtke A. 1992. Genetic characterization of the secretory mutant MS-1 of tetrahymena thermophila: Vacuolarization and block in secretion of lysosomal hydrolases are caused by a single gene mutation. Dev Genet 13(2):167-73. Hunseler P, Tiedtke A, von Figura K. 1988. Biosynthesis of secreted beta-hexosaminidase in tetrahymena thermophila. A comparison of the wild type with a secretory mutant. Biochem J 252(3):837-42. Hunseler P, Scheidgen-Kleyboldt G, Tiedtke A. 1987. Isolation and characterization of a mutant of tetrahymena thermophila blocked in secretion of lysosomal enzymes. J Cell Sci 88 ( Pt 1):47-55. |
Comments | Block in secretion is caused by a single gene mutation. Block in secretion and the expression of a vacuolarized phenotype are most probably controlled by the same sec allele. Low fertility. |
Research Resource Identifier | TSC_SD01785 |
Requires MTA? | No |
Academic cost | $45 |