Skip to main content

Follow @TetrahymenaSC

Stock IDSD01511
Strain NameIA123
SpeciesT. thermophila
Genetic DescriptioncdaC-2/cdaC-2 (cdaC-2; VII)
MAC Knockins/outs
MIC Knockins/outs
Gene of InterestCDAC (cell division arrest C) Originally published as mo3b
OriginF3 following outcross to B1868 VI of an assortant derived from nitroso-guanidine mutagenesis of B1868 VI x VII in 1973. It was originally believed to require homozygosity of alleles at two genes for full expression, but a second set of crosses gave results consistent with homozygosity for a single recessive allele being sufficient.
Frankel J, Jenkins LM, Doerder FP, Nelsen EM. 1976. Mutations affecting cell division in tetrahymena pyriformis. I. selection and genetic analysis. Genetics 83(3):489-506.

Frankel J, Nelsen EM, Jenkins LM. 1977. Mutations affecting cell division in tetrahymena pyriformis, syngen 1. II. phenotypes of single and double homozygotes. Dev Biol 58(2):255-75.
CommentsFailure to complete cytokinesis accompanied by cell elongation (>36o C). Located on chromosome 5. Allelic to cdaC-1 (IA-119). Expresses 100% fission blockage at temperatures of 36o C. and higher.

Submitted by Joseph Frankel, University of Iowa
Research Resource IdentifierTSC_SD01511
Requires MTA?No
Academic cost $35