Tetrahymena Stock Center| Stock ID | SD01460 |
| Strain Name | IA313 |
| AKA | big1-1 II |
| Species | T. thermophila |
| Genetic Description | big1-1/big1-1 (big1-1; II) |
| MAC Knockins/outs | |
| MIC Knockins/outs | |
| Gene of Interest | BIG1 (big 1) |
| Origin | Genomic exclusion progeny following 2 successive generations of outcrossing to B2079-X-II (with an intervening genomic exclusion cross) of a mutant clone resulting from nitrosoguanidine mutagenesis of IA264 in 1981 followed by cytogamy |
| Publications | Frankel J, Jenkins LM, Bakowska J, Nelsen EM. 1984b. Mutational analysis of patterning of oral structures in tetrahymena. I. effects of increased size on organization. J Embryol Exp Morphol 82:41-66. |
| Comments | Increase in size of cells, number of ciliary rows, and size of oral apparatus. Ciliary rows are disorganized, and 10-20% of oral apparatuses are abnormal, with extra membranelles common. Highly pleiotropic. The disorganization of the ciliary rows was not mentioned in the brief published description, but is prominent. Expression unform at all temperatures tested. Submitted by Joseph Frankel, University of Iowa |
| Research Resource Identifier | TSC_SD01460 |
| Requires MTA? | No |
| Academic cost | $45 |
