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Stock IDSD01456
Strain NameIA466
AKAhpo1-1 IIc
SpeciesT. thermophila
Genetic Descriptionhpo1-1/hpo1-1 (hpo1-1; II)
MAC Knockins/outs
MIC Knockins/outs
Gene of InterestHPO1 (hypoangular)
OriginGenomic exclusion progeny following an outcross in 1993 of hpo IIa (IA393) to B2086 VIb. IA393 was itself a genomic exclusion progeny following an outcross to IA264 of a mutant clone resulting from nitrosoguanidine mutagenesis of IA264 in 1988 followed by cytogamy.
PublicationsParental stock IA393 (hpo1 IIa) described in Frankel J, Jenkins LM, Nelsen EM, Stoltzman CA. 1993. Hypoangular: A gene potentially involved in specifying positional information in a ciliate, tetrahymena thermophila. Dev Biol 160(2):333-54. IA466 has the same cortical phenotype as IA393, but (unlike IA393) has a normal rate of culture growth
CommentsComplex phenotype with contractile vacuole pores too close to the oral apparatus, and clockwise slippage of oral primordia. Located on chromosome 3, probably 3R. The phenotype is mild at 28°, much more extreme at 39°. Allelic to hpo1-3 (IA 443).

Submitted by Joseph Frankel, University of Iowa
Research Resource IdentifierTSC_SD01456
Requires MTA?No
Academic cost $35