Stock ID | SD00629 |
Strain Name | IA219 |
AKA | disA-1 VII |
Species | T. thermophila |
Genetic Description | disA-1/disA-1 (disA-1; disA, VII) |
MAC Knockins/outs | |
MIC Knockins/outs | |
Gene of Interest | DISA (disorganized A) |
Origin | Homozygous F2 clones, obtained following an outcross to B1868 VII of an assortant derived from nitrosoguanidine mutagenesis of B1868 VI x VII in 1973, were crossed to each other in 1978 to obtain a F3 homozygote that was then crossed in 1979 to A-star to obtain an "F4" homozygote. Sister to IA217. |
Publications | Gene: Bruns PJ, Brussard TB, Merriam EV. 1983. Nullisomic tetrahymena. II. a set of nullisomics define the germinal chromosomes. Genetics 104(2):257-70. This clone: Jerka-Dziadosz M, Jenkins LM, Nelsen EM, Williams NE, Jaeckel-Williams R, Frankel J. 1995. Cellular polarity in ciliates: Persistence of global polarity in a disorganized mutant of tetrahymena thermophila that disrupts cytoskeletal organization. Dev Biol 169(2):644-61. |
Comments | disA-1 is a partially ts mutation that brings about disorganization of ciliary rows, without affecting the positioning of major cortical landmarks, or cytokinesis. |
Research Resource Identifier | TSC_SD00629 |
Requires MTA? | No |
Academic cost | $45 |